Acute carbon monoxide poisoning alters hemorheological parameters in human

作者：Ozturk Baris^*; Arihan Okan; Coskun Figen; Dikmenoglu Falkmarken Neslihan H

来源：Clinical Hemorheology and Microcirculation, 2016, 61(4): 591-597.

DOI：10.3233/CH-141919

• Hemorheology
• plasma viscosity
• erythrocyte deformability
• erythrocyte aggregation
• hematocrit
• acute carbon monoxide poisoning

Acute carbon monoxide (CO) poisoning seriously hinders oxygen delivery to tissues. This harmful effect of CO may be aggravated by accompanying changes in the viscosity of blood. We had previously reported increased plasma viscosity in people chronically exposed to CO. This study was planned to test our hypothesis that acute CO poisoning increases blood viscosity. For this purpose four main parameters contributing to blood viscosity -hematocrit, erythrocyte deformability, erythrocyte aggregation and plasma viscosity - were determined in patients with acute CO poisoning and compared with healthy controls. Plasma viscosity and erythrocyte aggregation tendency were lower in the CO group (p < 0.05). Erythrocyte deformability was also lower in CO group (p < 0.05). Our results indicate that acute CO poisoning has diverse effects on hemorheological parameters such as attenuating hematocrit value, plasma viscosity, erythrocyte aggregation tendency and erythrocyte deformability.

• 出版日期2016