A Mannich-Type Reaction at the meso-Methyl Position of the BODIPY Fluorophore

作者：Yang Lijing; Yan Hongbin^*

来源：Synlett, 2012, (10): 1526-1528.

DOI：10.1055/s-0031-1290669

• BODIPY
• Mannich reaction
• fluorophore
• dihalomethane
• secondary amine

Treatment of 2,6-diethyl-4,4-difluoro-1,3,5,7,8-pentamethyl-4-bora-3a, 4a-diaza-s-indacene (BODIPY) with secondary amines in dihalomethane resulted in carbon-carbon bond formation at the meso-methyl position of BODIPY via Mannich-type reactions. The resulting modified BODIPY fluorophores possess high fluorescent quantum yields.

• 出版日期2012-6