Dupuytren Disease Infiltrating a Full-Thickness Skin Graft

作者：Wade Ryckie George; Igali Laszlo; Figus Andrea^*

来源：Journal of Hand Surgery-American Volume, 2016, 41(8): E235-E238.

DOI：10.1016/j.jhsa.2016.04.011

• Dupuytren
• fibromatosis
• dermofasciectomy
• skin
• recurrence

Although the role of the skin in the development and propagation of Dupuytren disease remains unclear, dermofasciectomy and full-thickness skin grafting (FTSG) appears to delay recurrence. In 2011, a 71-year-old, left-handed man presented with recurrent Dupuytren disease in the dominant hand. In 1991, he originally underwent a primary dermofasciectomy and FTSG for Dupuytren disease involving the palmar skin. Twenty years later, the left middle finger was drawn into flexion by a recurrent cord, and the old graft and adjacent palmar skin were clinically involved by fibromatosis. We performed a revision dermofasciectomy and FTSG. Microscopic analysis of the excised graft demonstrated dense infiltration of the entire skin graft by Dupuytren disease, with areas of active and burnt-out fibromatosis distinct from hypertrophic scarring. This report of Dupuytren fibromatosis infiltrating a skin graft raises questions about the pathophysiology of Dupuytren disease.

• 出版日期2016-8