Arp2/3 and scar: Plants move to the fore

作者:Deeks MJ; Hussey PJ*
来源:Nature Reviews Molecular Cell Biology, 2005, 6(12): 954-964.
DOI:10.1038/nrm1765

摘要

The actin-nucleating Arp2/3 complex is essential for life in yeast and animals, but not in plants, in which mutants of Arp2/3 complex components show relatively minor developmental abnormalities. Animal cells control the activity of the Arp2/3 complex through the suppressor of cyclic AMP receptor ( SCAR) complex to achieve cell motility. Amazingly, plants have also retained the SCAR cell-motility pathway, and now provide a unique model for the study of new aspects of SCAR function in the absence of cell motility.

  • 出版日期2005-12