Acute simulated soccer-specific training increases PGC-1 alpha mRNA expression in human skeletal muscle

作者：Jeong Tae Seok; Bartlett Jonathan D; Joo Chang Hwa; Louhelainen Jari; Close Graeme L; Morton James P; Drust Barry^*

来源：Journal of Sports Sciences, 2015, 33(14): 1493-1503.

DOI：10.1080/02640414.2014.992937

• vastus lateralis
• cell signalling
• intermittent exercise

The aim of the current study was to quantify oxygen uptake, heart rate and molecular responses of human skeletal muscle associated with mitochondrial biogenesis following an acute bout of simulated soccer training. Muscle biopsies (vastus lateralis) were obtained from nine active men immediately pre-completion, post-completion and 3h post-completion of a laboratory-based soccer-specific training simulation on a motorised treadmill. The soccer-specific simulation was a similar intensity (55 +/- 6%
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) and duration (60min) as that observed in professional soccer training (e.g. standing 41%, walking 37%, jogging 11%, high-speed running 9% and sprinting 2%). Post-exercise, muscle glycogen decreased (Pre; 397 +/- 86mmol center dot kg(-1) dw, Post; 344 +/- 64mmol center dot kg(-1) dw; P=0.03), plasma lactate increased (P<0.001) up to ~4-5mmol center dot L-1, non-esterified fatty acids and glycerol increased (P<0.001) to values of 0.6 +/- 0.2mmol center dot L-1 and 145 +/- 54 mu mol center dot L-1, respectively. PGC-1 alpha mRNA increased (P=0.009) fivefold 3h post-exercise. We provide novel data by demonstrating that soccer-specific training is associated with increases in PGC-1 alpha mRNA. These data may have implications for practitioners in better understanding the metabolic and muscle responses to soccer-specific training protocols in the field.

• 出版日期2015-8-27