A role for BDNF in cocaine reward and relapse

作者：Schoenbaum Geoffrey^*; Stalnaker Thomas A; Shaham Yavin

来源：Nature Neuroscience, 2007, 10(8): 935-936.

DOI：10.1038/nn0807-935

Brain-derived neurotrophic factor (BDNF) is important in regulating synaptic plasticity in the brain areas that process reward information. A new study reports that BDNF in the nucleus accumbens, a brain area critical for the rewarding effects of cocaine, promotes persistent cocaine-seeking behaviors and heightens relapse vulnerability.

• 出版日期2007-8