A novel method to synthesize hydroxyapatite coating with hierarchical structure

作者：Lin, Dong-Yang^*; Wang, Xiao-Xiang

来源：Colloids and Surfaces B: Biointerfaces , 2011, 82(2): 637-640.

DOI：10.1016/j.colsurfb.2010.09.025

• Hydroxyapatite
• Coatings
• Hierarchical structure

A novel process has been developed for the preparation of a hydroxyapatite (HA) coating with a hierarchical structure on a Ti substrate. The Ti substrate was first subjected to electrolytic deposition at -1.6 V (versus Ag/AgCl/KCl) in a solution of 0.042 M Ca(NO3)(2)center dot 4H(2)O and 0.025 M NH(4)H(2)PO(4) at 85 degrees C for 3 min, and then post-treated in a 0.25 M NaOH solution, with the addition of 0.05 M Na(3)Cit at 85 degrees C for 5 h. The experimental results showed that the coating experienced a phase conversion from octacalcium phosphate to HA after the post-treatment step. The HA coating had well-distributed, micro-sized pores comprising three-dimensional interconnected mesoporous HA belts, which would greatly increase the porosity and surface area of the coating.

• 出版日期2011-2-1
• 单位浙江大学