Determination of DL-Methionine with Electro-chemiluminescence Molecularly Imprinting Method

作者：Du, Zhen; Fan, Chenling^*

来源：Asian Journal of Chemistry, 2014, 26(16): 5168-5170.

DOI：10.14233/ajchem.2014.16599

• Electro-chemiluminescence
• Molecularly imprinting method
• DL-Methionine

In order to establish a novel EC-MIP method in the determination of DL-methionine in human urine, a carbon electrode of [Ru(bpy)(3)](2+) was modified with the molecular imprinting polymers electro-deposited with the sol-gel method. The abilities of the electrochemical and electro-chemiluminescence characteristics of the above electrode were then investigated with the quantitative determination of dL-methionine in human urine. The method exhibited the high sensitivity and excellent selectivity towards DL-methionine. With the optimized conditions, the linear range of dL-methionine was from 1 x 10(-11) mol/L to 1 x 10(-8) mol/L, with the LOD as 2.6 x 10(-12) mol/L. This method could be successfully applied to the determination of dL-methionine in human urine samples for the precaution of certain diseases.

• 出版日期2014-8
• 单位中国医科大学