A Ru-II-TAP Complex, Photoreagent for Tryptophan-Containing Peptides: Structure of the Covalent Photoadduct

作者：Gauthier Nicolas; De Winter Julien; Gerbaux Pascal; Moucheron Cecile; Luhmer Michel^*; Kirsch De Mesmaeker Andree

来源：Inorganic Chemistry, 2010, 49(15): 6796-6798.

DOI：10.1021/ic101151e

We report the first structure determination of a covalent photoadduct between a Ru-II-tap complex and a tryptophan-containing peptide (AlaTrpAla) by mass spectrometry and NMR spectroscopy. Ru-II-tap complexes could thus be exploited as photodamaging agents of Trp-containing polypeptides or proteins.

• 出版日期2010-8-2