A facile base-mediated synthesis of N-alkoxy-substituted benzimidazoles

作者：Ansari Nurul H; Jordan Arica L; Soderberg Bjorn C G^*

来源：Tetrahedron, 2017, 73(32): 4811-4821.

DOI：10.1016/j.tet.2017.06.063

• N-alkoxybenzimidazole
• Base-mediated synthesis
• Enamines

Base mediated cyclization of enamines derived from condensation of 2-nitroanilines with alpha-branched aldehydes, in the presence of an electrophile, affords N-alkoxy-substituted benzimidazoles with or without an oxygenate side chain in the 2-position.

• 出版日期2017-8-10