Adverse events associated with laparoscopy vs laparotomy in the treatment of endometrial cancer

作者：Barnett Jason C^*; Havrilesky Laura J; Bondurant Amy E; Fleming Nicole D; Lee Paula S; Secord Angeles Alvarez; Berchuck Andrew; Valea Fidel A

来源：American Journal of Obstetrics and Gynecology, 2011, 205(2): 143.e1.

DOI：10.1016/j.ajog.2011.03.012

• endometrial cancer
• laparoscopy
• surgical complications

OBJECTIVE: The objective of the study was to compare adverse event rates between laparoscopic vs open surgery for endometrial cancer.
STUDY DESIGN: This was a retrospective cohort study comparing 107 women who underwent laparoscopy with 269 age-and body mass index-matched women who underwent laparotomy for treatment of endometrial cancer.
RESULTS: Adverse event rates were similar between cohorts (37% laparoscopy vs 43% laparotomy, P = .248). Laparotomies had higher rates of cellulitis (16% vs 7%, P = .018) and open wound infection (9% vs 2%, P = .02), whereas laparoscopy had higher rates of sensory peripheral nerve deficit (5% vs 0%, P = .008) and lymphedema (7% vs 1%, P = .003). Laparoscopy was associated with longer mean operating room times but with shorter hospital stays and lower mean blood loss.
CONCLUSION: Laparoscopy was associated with decreased rates of surgical site infections but had an increased risk of peripheral sensory nerve deficits and lymphedema when compared with laparotomy.

• 出版日期2011-8