Directing Self-Assembly of DNA Nanotubes Using Programmable Seeds

作者：Mohammed Abdul M; Schulman Rebecca^*

来源：Nano Letters, 2013, 13(9): 4006-4013.

DOI：10.1021/nl400881w

• DNA nanotubes
• DNA origami
• self-assembly
• programmable nanostructures
• controlling nanotube growth
• programming nanotube circumference

Control over when and where nanostructures arise is essential for the self-assembly of dynamic or multicomponent devices. We design and construct a DNA origami seed for the control of DAE-E tile DNA nanotube assembly. Seeds greatly accelerate nanotube nucleation and growth because they serve as nanotube nucleation templates. Seeds also control nanotube circumference. Simulations predict nanotube growth rates and suggest a small nucleation barrier remains when nanotubes grow from seeds.

• 出版日期2013-9