ALBUMIN AS A DRUG DELIVERY AND DIAGNOSTIC TOOL AND ITS MARKET APPROVED PRODUCTS

作者：Sethi Ayesha; Sher Muhammad; Akram Muhammad Rouf; Karim Sabiha; Khiljee Sonia; Sajjad Ashif; Shah Syed Nisar Hussain; Murtaza Ghulam^*

来源：Acta Poloniae Pharmaceutica, 2013, 70(4): 597-600.

• albumin
• drug delivery tool
• peptides
• radiopharmaceutical

Albumin is one of the most extensively studied endogenous proteins which are used in the fabrication of drug delivery and diagnostic technologies during last 10 years. This review provides a summary of products involving the use of albumin as a drug delivery tool for getting better the pharmacokinetics of a drug by developing the targetted drug delivery systems and diagnosing the pathologies. Using albumin, following market approved products have been developed: Levemir (R) and Victoza (R) (antidiabetic product), Abraxane (R) (antimetastatic breast cancer product), and Nanocoll (R) and Albures (R) (for lymphoscintigraphy and diagnosis of cancer and rheumatoid arthritis).

• 出版日期2013-8