A new synthesis of pyrrolo[1,2-c]quinazoline from quinazolinium N-ylides: a re-investigation

作者：Georgescu Emilian; Georgescu Florentina; Caira Mino R; Nicolescu Alina; Deleanu Calin; Danila Mariana G; Filip Petru; Dumitrascu Florea^*

来源：ARKIVOC, 2009, 2009(12): 232-241.

DOI：10.3998/ark.5550190.0010.c20

• Quinazolinium-3-methylides
• pyrrolo[1,2-c]quinazoline
• NOE experiments

The structure of the products obtained when generating quinazolinium-3-methylides in the absence of an activated alkyne has been investigated using X-ray diffraction and NOE experiments in high resolution NMR. All data are in agreement with a pyrrolo[1,2-c]quinazoline structure having aromatic and benzoyl substituents in positions 2 and 3 respectively, and a hydrogen in position 1, in contrast to previous assignments with hydrogen in position 3.

• 出版日期2009