A First Glimpse of Nucleation of Phase Transitions in Living Cells

作者：Posey Ammon E; Pappu Rohit V^*

来源：Molecular Cell, 2018, 71(1): 1-3.

DOI：10.1016/j.molcel.2018.06.028

Prion formation and propagation involve the nucleation and growth of protein-based supramolecular assemblies. In this issue of Molecular Cell, Khan et al. (2018) report novel methods that enable quantitative, high-throughput analyses of nucleation of supramolecular assemblies by prion-forming proteins in living cells. Their approaches turn living cells into veritable test tubes for biophysical investigations.

• 出版日期2018-7-5