Acetophenones from Acronychia pedunculata and their Cancer Chemopreventive Activity

作者：Ito Chihiro; Hosono Mari; Tokuda Harukuni; Wu Tian Shung; Itoigawa Masataka^*

来源：Natural Product Communications, 2016, 11(9): 1299-1302.

DOI：10.1177/1934578x1601100929

• Acronychia pedunculata
• Rutaceae
• Acrophenone D
• Acrophenone E
• Acrophenone F
• Chemopreventive activity

From the roots of Acronychia pedunculata (L.) Miq. (Rutaceae) collected in Taiwan, six known and three new acetophenones have been isolated. The new compounds were named acrophenones D (1), E (2), and F (3). Of the acetophenones isolated in this study, prenylacronylin (4) and acronyculatin D (10) exhibited significant inhibitory activity against 12-0-tetradecanoylphorbol 13-acetate-induced Epstein-Barr virus early antigen activation in Raji cells.

• 出版日期2016-9