A new method of controlled grafting modification of chitosan via nitroxide-mediated polymerization using chitosan-TEMPO macroinitiator

作者：Hua Daoben^*; Deng Weicai; Tang Jing; Cheng Jianxin; Zhu Xiulin

来源：International Journal of Biological Macromolecules, 2008, 43(1): 43-47.

DOI：10.1016/j.ijbiomac.2007.12.009

• chitosan
• modification
• graft copolymers
• nitroxide-mediated polymerization (NMP)

The controlled graft modification of chitosan has first been achieved by nitroxide-mediated polymerization using chitosan-TEMPO macroinitiator. Chitosan-TEMPO macroinitiator was obtained from the Co-60 gamma-ray irradiation of N-phthaloylchitosan and 4-hydroxy-TEMPO in DMF under argon atmosphere. The graft copolymers were characterized by H-1 nuclear magnetic resonance (H-1 NMR), Fourier transform infrared spectrometer (FTIR), X-ray powder diffractometer (XRD) and high performance particle sizer (HPPS). The results indicate that the graft copolymers were successfully synthesized and that the graft polymerization was well controlled by the nitroxide-mediated process. The size distribution of chitosan-g-polystyrene in benzene is very narrow, which may be associated with the "well-defined" polystyrene (PSt) onto chitosan from nitroxide-mediated polymerization. This work provides a new method to prepare chitosan grafting copolymers with controlled molecular weights and "well-defined" structures.

• 出版日期2008-7-1
• 单位宿州学院; 苏州大学