Birth weight and maternal socioeconomic circumstances were inversely related to systolic blood pressure among Afro-Caribbean young adults

作者：Ferguson Trevor S^*; Younger Coleman Novie O; Tulloch Reid Marshall K; Knight Madden Jennifer M; Bennett Nadia R; Samms Vaughan Maureen; Ashley Deanna; McCaw Binns Affette; Molaodi Oarabile R; Cruickshank J Kennedy; Harding Seeromanie; Wilks Rainford J

来源：Journal of Clinical Epidemiology, 2015, 68(9): 1002-1009.

DOI：10.1016/j.jclinepi.2015.01.026

• Birth weight
• Fetal growth
• Blood pressure
• Socioeconomic factors
• Young adult
• Jamaica
• Black
• Caribbean

Objectives: In this study, we examined the effects of birth weight (BWT) and early life socioeconomic circumstances (SEC) on systolic blood pressure (SBP) and diastolic blood pressure (DBP) among Jamaican young adults.
Study Design and Setting: Longitudinal study of 364 men and 430 women from the Jamaica 1986 Birth Cohort Study. Information on BWT and maternal SEC at child's birth was linked to information collected at 18-20 years old. Sex-specific multilevel linear regression models were used to examine whether adult SBP/DBP was associated with BWT and maternal SEC.
Results: In unadjusted models, SBP was inversely related to BWT z-score in both men (beta, -0.82 mm Hg) and women (beta, -1.18 mm Hg) but achieved statistical significance for women only. In the fully adjusted model, one standard deviation increase in BWT was associated with 1.16 mm Hg reduction in SBP among men [95% confidence interval (Cl): 2.15, 0.17; P = 0.021] and 1.34 mm Hg reduction in SBP among women (95% Cl: 2.21, 0.47; P = 0.003). Participants whose mothers had lower SEC had higher SBP compared with those with mothers of high SEC (beta, 3.4-4.8 mm Hg for men, P < 0.05 for all SEC categories and 1.8-2.1 for women, P > 0.05).
Conclusion: SBP was inversely related to maternal SEC and BWT among Jamaican young adults.

• 出版日期2015-9