An operationally simple green procedure for the synthesis of dihydropyrimido[4,5-d]pyrimidinetriones using CuI nanoparticles as a highly efficient catalyst

作者：Abdolmohammadi Shahrzad^*; Afsharpour Maryam

来源：Zeitschrift Fur Naturforschung Section B-a Journal of Chemical Sciences, 2015, 70(3): 171-176.

DOI：10.1515/Znb-2014-0207

• aqueous media
• CuI nanoparticles (CuI NPs)
• dihydropyrimido[4,5-d]pyrimidinetriones
• reusability of catalyst

A green, efficient and simple protocol was developed for the synthesis of dihydropyrimido[4,5-d]pyrimidinetrione derivatives via a coupling reaction of 6-aminouracils, aromatic aldehydes and urea in aqueous media in the presence of nano-crystalline CuI at room temperature. The products were obtained in high yields. CuI nanoparticles can be recycled three times without significant loss of catalytic activity.

• 出版日期2015-3