科研之友
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摘要
One new polyacetylene glycoside eprostrata ROMAN NUMERAL ONE (1), together with seven known compounds (2-8), were isolated from Eclipta prostrata. Their structures were elucidated on the basis of spectroscopic and physico-chemical analyses. All the isolates were evaluated inhibitory activity on DGAT in an in vitro assay. Compounds 1-8 were found to exhibit inhibitory activity of DGAT1 with IC50 values ranging from 74.4 +/- 1.3 to 101.1 +/- 1.1 mu M. [GRAPHICS] .
- 出版日期2019-6-3
- 单位北华大学
