Association of H-Type Hypertension with Stroke Severity and Prognosis

作者：Li, Tan; Zhu, Jiajia; Fang, Qi; Duan, Xiaoyu; Zhang, Mingzhi; Diao, Shanshan; Zhou, Yun; Yang, Si; Kong, Yan^*; Cai, Xiuying^*

来源：Biomed Research International, 2018, 2018: 8725908.

DOI：10.1155/2018/8725908

• HOMOCYSTEINE LEVELS
• ISCHEMIC-STROKE
• RISK
• MARKERS
• DISEASE

Background. The correlation between H-type hypertension and acute ischemic stroke remains uncertain. Objective. The present study was designed to explore the possible relationship between H-type hypertension and severity and prognosis of acute ischemic stroke. Method. We included 372 patients with acute ischemic stroke and divided them into four groups: H-type hypertension group, simple hypertension group, simple hyperhomocysteinemia (HHcy) group, and the control group. NIHSS score was measured at both admission and two weeks later. m RS score, stroke recurrence, cardiovascular event, or all-cause mortality was recorded at 3-month and 1-year follow-up. Result. The results showed that the NIHSS score on admission in the H-type hypertension group (6.32 +/- 5.91) was significantly higher than that in the control group (3.97 +/- 3.59) (P < 0.05), while there was no obvious association between H-type hypertension and NIHSS score after 2-week treatment (P = 0.106). Endpoint events incidence in H-type hypertension group was the highest; however, in the cox regression model of multiple factor analysis, H-type hypertension was not an independent risk factor. Conclusion. H-type hypertension may result in early functional deterioration and higher incidence rate of endpoint events but not act as an independent risk factor.

• 出版日期2018
• 单位苏州大学