Upper Airway Surgery for Obstructive Sleep Apnea Reduces Blood Pressure

作者：Pang Kenny P^*; Pang Edward B; Pang Kathleen A^*; Vicini Claudio; Chan Yiong Huak; Rotenberg Brian W

来源：Laryngoscope, 2018, 128(2): 523-527.

DOI：10.1002/lary.26759

• Blood pressure
• upper airway surgery
• obstructive sleep apnea

Objectives/Hypothesis: To evaluate if upper airway surgery reduces blood pressure in patients with obstructive sleep apnea (OSA).
Study Design: Prospective series.
Methods: A prospective series of 112 consecutive OSA patients with hypertension (HTN). All patients were> 18 years old, respiratory disturbance index >5, all levels of apnea-hypopnea index (AHI), with a history of HTN treated with medication for at least 6 months. Surgical procedures included septoplasty, turbinate reduction, palate surgery, and tongue base reduction.
Results: There were 92 men and 20 women, with a mean age of 48.6 years, mean body mass index (BMI) was 27.5 (range, 19.7-34.7). Mean follow-up was 16.1 months. The mean preoperative AHI was 32.6 (range, 1.2-104), with the mean lowest oxygen saturation (LSAT) of 79.9% (range, 52%-93%). The mean adjusted preoperative and postoperative systolic blood pressure (SBP) was reduced from 146 +/- 15.3 mm Hg to 122 +/- 12.5 mm Hg (P <.001), and diastolic blood pressure (DBP) was reduced from 91 +/- 10.2 mm Hg to 76 +/- 7.8 mm Hg (P <.001). There was a decrease in overall BMI from 27.5 +/- 3.6 to 25.5 +/- 3.0 (P <.001); however, based on multivariate analysis, the reduction in SBP and DBP was not affected by this BMI reduction. Fifty-eight patients (51.8%) did not require their antihypertensive after surgery. There was poor correlation noted between HTN with AHI, LSAT, and oxygen duration <90%.
Conclusions: Upper airway surgery does reduce SBP and DBP in patients with OSA.

• 出版日期2018-2