Deuterium Oxide (D2O) Determination in Water by Gas Chromatography-Mass Spectrometry Following Deuterium Exchange Headspace Extraction

作者：Hassan Jalal^*; Farahani Abolfazl; Ramezani Majid

来源：Journal of Analytical Chemistry, 2018, 73(8): 796-800.

DOI：10.1134/S1061934818080063

• heavy water
• headspace extraction
• gas chromatography-mass spectrometry
• deuterium exchange

A reliable, simple and fast method for quantitative analysis of heavy water (D2O) was developed using deuterium exchange headspace extraction-gas chromatography-mass spectrometry. The method is based on incubating the acetic anhydride with D2O, CH3COOD formation, headspace extraction of CH3COOD (exchange of hydrogen for deuterium) and gas chromatography/mass spectrometry detection. The quantification was performed using single ion monitoring (m/z = 61). The calibration was linear (R (2) = 0.9998) in the concentration range of 1 x 10(3)-3 x 10(5) mg/L). This method can measure D2O concentrations in water from 0.27 g/L. It was applied for determination of D2O in distilled water with accuracy RSD 6% and precision RSD <= 4%.

• 出版日期2018-8