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摘要
Association characteristics of amphiphilic phenothiazine drugs Fluphenazine and Trifluperazine dihydrochloride in water have been examined and their thermodynamic parameters have been calculated using conductometry. The electrical conductivity was measured as a function of concentration at various temperatures and cmc was calculated in the temperature range of 20-50 degrees C. Thermodynamic parameters i. e. standard free energy of micellization, Delta G(m)degrees, standard enthalpy of micellization, Delta H-m degrees. and standard entropy of micellization, Delta S-m. were calculated from cmc value using closed association model.
- 出版日期2013-9
