Asymmetric Pauson-Khand-type reaction mediated by Rh(I) catalyst at ambient temperature

作者：Kim Dong Eun; Kim In Su; Ratovelomanana Vidal Virginie^*; Genet Jean Pierre; Jeong Nakcheol

来源：Journal of Organic Chemistry, 2008, 73(20): 7985-7989.

DOI：10.1021/jo801236c

An efficient asymmetric PKR mediated by Rh(I) catalyst at ambient temperature was developed. The reaction utilizing a Rh(I) catalyst bearing a (R)-3,5-diMeC(4)H(4)-BINAP ligand at 18-20 degrees C under a reduced partial pressure of CO (0.1 atm) provided PKR products in high chemical yield as well as high enantioselectivity.

• 出版日期2008-10-17