A microfluidic approach for high-throughput droplet interface bilayer (DIB) formation

作者：Stanley C E; Elvira K S; Niu X Z; Gee A D; Ces O^*; Edel J B; deMello A J

来源：Chemical communications, 2010, 46(10): 1620-1622.

DOI：10.1039/b924897h

We present a simple, automated method for high-throughput formation of droplet interface bilayers (DIBs) in a microfluidic device. We can form complex DIB networks that are able to fill predefined three dimensional architectures. Moreover, we demonstrate the flexibility of the system by using a variety of lipids including 1,2-diphytanoyl-sn-glycero-3-phosphocholine ( DPhPC) and 1,2-dioleoyl-sn-glycero-3-phosphocholine ( DOPC).

• 出版日期2010