A review of adenoid cystic carcinoma of the breast with emphasis on its molecular and genetic characteristics

作者：Vranic Semir; Bender Richard; Palazzo Juan; Gatalica Zoran^*

来源：Human Pathology, 2013, 44(3): 301-309.

DOI：10.1016/j.humpath.2012.01.002

• Breast cancer
• Triple-negative breast carcinoma
• Special types
• Adenoid cystic carcinoma

Breast carcinomas that do not express estrogen receptor alpha, progesterone receptor, or human epidermal growth factor receptor 2 are frequently grouped together as "triple negative" and considered an aggressive type of breast malignancy; however, this group is not homogeneous. Adenoid cystic carcinoma of the breast is a rare type of breast cancer with such triple-negative features and, generally, a more favorable clinical course. This comprehensive review describes diagnostic, molecular, and clinical features of adenoid cystic carcinoma and compares them with those of triple-negative breast carcinomas of no special type.

• 出版日期2013-3