ACSF3 and Mal(onate)-Adapted Mitochondria

作者:Lombard David B*; Zhao Yingming*
来源:Cell Chemical Biology, 2017, 24(6): 649-650.
DOI:10.1016/j.chembiol.2017.06.004

摘要

In this issue of Cell Chemical Biology, Bowman and colleagues show that the mitochondrial enzyme ACSF3 generates malonyl-CoA from malonate, in turn regulating metabolic flux and mitochondrial protein malony-lation (Bowman et al., 2017). The study reveals a mechanism to generate mitochondrial malonyl-CoA and how this molecule impacts mitochondrial biology.

  • 出版日期2017-6-22