Diastereoselective Synthesis of Indanes via a Domino Stetter-Michael Reaction

作者:Sanchez Larios Eduardo; Gravel Michel*
来源:Journal of Organic Chemistry, 2009, 74(19): 7536-7539.
DOI:10.1021/jo901468h

摘要

N-Heterocyclic carbenes were found to catalyze a domino Stetter-Michael reaction for the synthesis of indanes. The products were obtained in good yield and diastereomeric ratio, allowing access to highly functionalized indanes under mild conditions. In addition, the functional groups present on the indanes could be used for the synthesis of polycyclic pyrroles.

  • 出版日期2009-10-2