Lantana camara Linn root extract-mediated gold nanoparticles and their in vitro antioxidant and cytotoxic potentials

作者：Ramkumar Rajendiran; Balasubramani Govindasamy; Raja Ramalingam Karthik; Raja Manickam; Govindan Raji; Girija Easwaradas Kreedapathy; Perumal Pachiappan

来源：Artificial Cells Nanomedicine and Biotechnology, 2017, 45(4): 748-757.

DOI：10.1080/21691401.2016.1276923

• Lantana camara
• Au NPs
• HR-TEM
• DPPH
• MDA-MB-231

The Lantana camara Linn root extract derived gold nanoparticles (Au NPs) were characterized by Ultraviolet-Visible spectroscopy, X-ray diffraction, fourier transform-infrared, high resolution transmission electron microscopy, selected area electron diffraction pattern and energy dispersive X-ray analyses. In DPPH assay, the inhibitory concentration (IC50) of Au NPs and gallic acid was 24.17 and 5.39g/ml, whereas, for cytotoxicity assay, the IC50 of Au NPs was 17.72 and 32.98g/ml on MBA-MB-231 and Vero cells, respectively. Thus, the Au NPs possess significant in vitro antioxidant and cytotoxic properties which could be considered as potential alternate for the development of anticancer drug in future.

• 出版日期2017-6