AN ANALYSIS OF SEASONALITY OF SARCOIDOSIS IN THE UNITED STATES VETERAN POPULATION: 2000-2007

作者：Gerke A K^*; Tang F; Yang M; Cavanaugh J E; Polgreen P M

来源：Sarcoidosis Vasculitis and Diffuse Lung Diseases, 2012, 29(2): 155-158.

• seasonality of sarcoidosis
• veteran population
• seasonal effects

Background: The onset of sarcoidosis is thought to be seasonal, particularly Lofgren%26apos;s syndrome. However, there are conflicting data on seasonality by country and by radiographic stage. Objective: The objective of this study was to determine if there is seasonality of the diagnosis of sarcoidosis in outpatients in the United States. Methods and Results: Using time series methods, we performed a retrospective analysis of 3791 incident cases of sarcoidosis in the Veteran%26apos;s Health Administration national outpatient claims database (20002007). We did not find overall seasonality in the occurrence of new sarcoidosis in United States Veterans (p=0.9860), even after we subdivided the United States by northern (p=0.6824) and southern regions (p=0.4588). Conclusion: The lack of seasonality in this study indicates that season is not a dominant factor in complex gene-environment-host interaction that precedes presentation of new sarcoidosis cases in the United States Veteran population.

• 出版日期2012