科研之友
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摘要
<正>Excitotoxicity is a process observed in many disease states by which an excessive synaptic excitation causes neuronal death,and is thought to be triggered by the extracellular accumulation of the excitatory neurotransmitter glutamate,which binds and activates ionotropic N-methyl-D-aspartate glutamatergic receptors(NMDARs)in the brain.Normally,NMDARs mediate calcium entry into the cell to regulate physiological processes such as synaptic plasticity and memory,
- 出版日期2016-11
