DECREASED INNATE IMMUNE CYTOKINE RESPONSES CORRELATE WITH DISEASE SEVERITY IN CHILDREN WITH RESPIRATORY SYNCYTIAL VIRUS AND HUMAN RHINOVIRUS BRONCHIOLITIS

作者：Garcia Carla; Soriano Fallas Alejandra; Lozano Juanita; Leos Nora; Gomez Ana M; Ramilo Octavio; Mejias Asuncion^*

来源：Pediatric Infectious Disease Journal, 2012, 31(1): 86-89.

DOI：10.1097/INF.0b013e31822dc8c1

• RSV
• HRV
• innate immunity
• cytokines
• disease severity
• Bronchiolitis

The immunopathogenesis of respiratory syncytial virus (RSV) and human rhinovirus lower respiratory tract infections in children remains to be defined. We measured nasal wash concentrations of 29 cytokines in infants with RSV or human rhinovirus lower respiratory tract infections. Concentrations of interferon-gamma in RSV and innate immunity cytokines in both infections inversely correlated with disease severity.

• 出版日期2012-1