High Prevalence of Biocide Resistance Determinants in Staphylococcus aureus Isolates from Three African Countries

作者：Conceicao Teresa; Coelho Celine; de Lencastre Herminia; Aires de Sousa Marta

来源：Antimicrobial Agents and Chemotherapy, 2016, 60(1): 678-681.

DOI：10.1128/AAC.02140-15

We assessed the prevalence of six biocide resistance genes among 82 methicillin-resistant Staphylococcus aureus (MRSA) and 219 methicillin-susceptible S. aureus (MSSA) isolates from three African countries; the prevalence was very high for sepA (95.3%), mepA (89.4%), and norA (86.4%), intermediate for lmrS (60.8%) and qacAB (40.5%), and low for smr (3.7%). A significant association between biocide resistance genes and antibiotic resistance was observed, and a new cutoff MIC of >= 1 mg/liter for chlorhexidine nonsusceptibility was defined.

• 出版日期2016-1