Non-resective surgery and radiosurgery for treatment of drug-resistant epilepsy

作者：Romanelli Pantaleo^*; Striano Pasquale; Barbarisi Manlio; Coppola Giangennaro; Anschel David J

来源：Epilepsy Research, 2012, 99(3): 193-201.

DOI：10.1016/j.eplepsyres.2011.12.016

• Deep brain stimulation
• Epilepsy
• Vagal nerve stimulation
• Multiple subpial transections
• Neuromodulation
• Stereotactic radiosurgery

Epilepsy surgery is an effective treatment for properly selected patients with intractable seizures. However, many patients with medically intractable epilepsy are not excellent candidates for surgical resection of the epileptogenic zone. Due to recent advances in computer technology and bioengineering, several novel techniques are receiving increasing interest for their rote in the care of people with epilepsy. Neuromodulation is an emerging surgical option to be used when conventional resective surgery is not indicated. We review the indications and expected outcomes of neuromodulatory treatments currently available for the treatment of refractory epilepsy, i.e., vagus nerve stimulation, deep brain stimulation, stereotactic radiosurgery, and multiple subpial transections.

• 出版日期2012-5