Down's syndrome and Alzheimer's disease: towards secondary prevention

作者:Ness Seth*; Rafii Michael; Aisen Paul; Krams Michael; Silverman Wayne; Manji Husseini
来源:Nature Reviews Drug Discovery, 2012, 11(9): 655-656.
DOI:10.1038/nrd3822

摘要

A public-private partnership to establish biomarkers of dementia in Down's syndrome could aid the development of preventive therapies for the dementia associated with both Down's syndrome and Alzheimer's disease, based on the apparent common pathogenic role of amyloid precursor protein in the two conditions.

  • 出版日期2012-9