Analytical separation of Au/Ag core/shell nanoparticles by capillary electrophoresis

作者：Liu Fu Ken^*; Tsai Ming Huei; Hsu Ya Chuan; Chu Tieh Chi

来源：Journal of Chromatography A, 2006, 1133(1-2): 340-346.

DOI：10.1016/j.chroma.2006.08.033

• capillary electrophoresis
• separation
• Au/Ag
• core/shell
• nanoparticles

This paper demonstrates that capillary electrophoresis (CE) can be employed for characterizing the sizes of a series of Au/Ag core/shell nanoparticles (NPs). We effected the CE separation of Au/Ag core/shell NPs using a mixed buffer of sodium dodecyl sulphate (SDS) (40 mM) and 3-(cyclohexylamino)propanesulfonic acid (10 mM) at pH 9.7 and an applied voltage of 20 kV. A linear relationship (R-2 > 0.99) existed between the electrophoretic mobilities and the sizes of the Au/Ag core/shell NPs within the diameter range from 25 to 90 nm; the relative standard deviations of these electrophoretic mobilities were < 0.9%. From the good correlation between the results obtained by CE and those provided by scanning electron microscopy, we confirmed that this CE method is a valid one for characterizing the sizes of Au/Ag core/shell NP samples. In addition, when the Au/Ag core/shell NPs were separated through CE and detected using an on-line photodiode array detector, this approach allowed the chemical characterization of the NP species. This CE approach should allow the rapid and cost-effective characterization of a number of future nanomaterials.

• 出版日期2006-11-10