Dioxin Concentrations in Breast Milk of Vietnamese Nursing Mothers: A Survey Four Decades after the Herbicide Spraying

作者：Pham The Tai^*; Nishijo Muneko; Kido Teruhiko; Nakagawa Hideaki; Maruzeni Shoko; Naganuma Rie; Nguyen Thi Nguyet Anh; Morikawa Yuko; Hoang Van Luong; Tran Hai Anh; Nguyen Ngoc Hung; Le Ke Son; Tawara Kenji; Nishijo Hisao

来源：Environmental Science & Technology, 2011, 45(15): 6625-6632.

DOI：10.1021/es201666d

In an operation by United States Armed Forces during 1961 to 1971, large quantities of herbicides were sprayed in South Vietnam. These herbicides contained 2,3,7,8-tetrachlorodibenzo-p-dioxin (2,3,7,8-tetraCDD), the most toxic congener of dioxins. Several decades after the herbicide spraying ceased, dioxin concentrations in the environment and human remained elevated in the sprayed areas. Breast milk samples from 520 nursing mothers residing in areas including the hot spots as well as the sprayed and unsprayed areas were collected to quantify the levels of dioxins. The total toxic equivalents of 2,3,7,8-substitued PCDDs/PCDFs in breast milk of mothers living in the hot spots, and the sprayed and unsprayed areas were 14.10 pg/g lipid, 10.89 pg/g lipid, and 4.09 pg/g lipid for primiparae and 11.48 pg/g lipid, 7.56 pg/g lipid, and 2.84 pg/g lipid for multiparae, respectively, with significant differences in the values among the three areas. In the hot spots, dioxin levels were highly correlated with die residency of mothers after adjustment for their age and parity.

• 出版日期2011-8-1
• 单位河北医科大学