First Example of Quinoxaline-Directed C-H Activation: A Novel Method for Acetoxylation of Arenes

作者：Reddy B V Subba^*; Ramesh K; Yadav J S

来源：Synlett, 2011, 2011(2): 169-172.

DOI：10.1055/s-0030-1259292

• hypervalent iodine reagent
• aryl quinoxalines
• acetoxylation
• C-H activation

2-Aryl- and 2,3-diarylquinoxalines undergo smooth acetoxylation in the presence of 5 mol% Pd(OAc)(2) and a stoichiometric amount of PhI(OAc)(2) via C-H activation to produce the corresponding acetoxy-susbstituted quinoxaline derivatives in excellent yields with high regioselectivity.

• 出版日期2011-1-11