Multiresidue determination of fluoroquinolones, organophosphorus and N-methyl carbamates simultaneously in porcine tissue using MSPD and HPLC-DAD

作者：Wang Shuting; Mu Hui^*; Bai Yanhong; Zhang Yanwei; Liu Honglang

来源：Journal of Chromatography B-Analytical Technologies in the Biomedical and Life Sciences, 2009, 877(27): 2961-2966.

DOI：10.1016/j.jchromb.2009.07.011

• Matrix solid-phase dispersion
• High performance liquid chromatography
• Fluoroquinolones
• Organophosphorus
• N-methyl carbamates
• Multiresidue

Increasing concerns on public health safety have led researchers to develop efficient methods to characterize veterinary drugs and pesticides residues simultaneously in animal products. This investigation presents a simple and rapid method to determine five types of fluoroquinolones (FQs), organophosphorus (OP) and N-methyl carbamates (NMCs) in porcine tissue simultaneously with the use of matrix solid-phase dispersion (MSPD), high performance liquid chromatography (HPLC) and diode array detection (DAD). The results show a recovery ratio of 60.1-107.7% with satisfactory relative standard deviations. The limits of detection (LOD) in porcine tissue are between 9 and 22 mu g/kg. The applicability of the method to the multiresidue analysis in porcine tissue is reported in this contribution.

• 出版日期2009-10-1
• 单位西安交通大学