Assessment of fatigue in a large series of 1492 Brazilian patients with Spondyloarthritis

作者：Bianchi Washington A; Elias Fernanda R; Carneiro Sueli; Bortoluzzo Adriana B; Goncalves Celio R; Braga da Silva Jose Antonio; Ximenes Antonio Carlos; Bertolo Manoel B; Ribeiro Sandra L E; Keiserman Mauro; Skare Thelma L; Menin Rita; Azevedo Valderilio F; Vieira Walber P; Albuquerque Elisa N; Bonfiglioli Rubens; Campanholo Cristiano; Carvalho Hellen M S; Costa Izaias P; Duarte Angela P; Kohem Charles L; Leite Nocy H; Lima Sonia A L; Meirelles Eduardo S

来源：Modern Rheumatology, 2014, 24(6): 980-984.

DOI：10.3109/14397595.2014.906049

• Spondyloarthritis
• Fatigue
• Disease activity
• Quality of life

Background. The aim of the present study was to analyze the score of fatigue in a large cohort of Brazilian patients with SpA, comparing different disease patterns and its association with demographic and disease-specific variables. %26lt;br%26gt;Methods. A common protocol of investigation was prospectively applied to 1492 Brazilian patients classified as SpA according to the European Spondyloarthropathies Study Group (ESSG) criteria, attended at 29 reference centers. Clinical and demographic variables were recorded. Fatigue was evaluated using the first item of the Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) questionnaire. %26lt;br%26gt;Results. The mean BASDAI fatigue score was 4.20 +/- 2.99. There was no significant difference in the fatigue score between the different SpA. Fatigue was higher in female patients (p %26lt; 0.001), with mixed (axial vertical bar peripheral) involvement (p %26lt; 0.001) and in those who did not practice exercises (p %26lt; 0.001). Higher scores of fatigue were significantly associated with inflammatory low back pain (p = 0.013), alternating buttock pain (p = 0.001), cervical pain (p = 0.001), and hip involvement (p = 0.005). Fatigue presented a moderate positive statistical correlation with Bath Ankylosing Spondylitis Functional Index (BASFI) (0.469; p %26lt; 0.001) and Ankylosing Spondylitis Quality of Life (0.462; p %26lt; 0.001). %26lt;br%26gt;Conclusion. In this large series of Brazilian SpA patients, higher fatigue scores were associated with female gender, sedentary, worse functionality, and quality of life.

• 出版日期2014-11