An efficient protocol for domino one pot synthesis of 1,2,3-triazoles from natural organic acids and phenols

作者：Dangroo Nisar A; Dar Alamgir A; Dar Bashir Ahmad^*

来源：Tetrahedron Letters, 2014, 55(49): 6729-6733.

DOI：10.1016/j.tetlet.2014.09.123

• Triazoles
• One-pot synthesis
• Domino approach
• Natural products
• Organic acids

An efficient three-component protocol was developed for the one-pot synthesis of 1,2,3-triazoles from natural product based acids and phenols, using CuSO4-sodium ascorbate catalyst system. The method is general and showed considerable synthetic advantage giving products in excellent yields with a wide substrate scope.

• 出版日期2014-12-3