A facile and cheap synthesis of zwitterion coatings of the CS@PGMA@IDA nanomaterial for highly specific enrichment of glycopeptides

作者：Zou, Xiajuan^*; Jie, Jianzheng; Yang, Bin

来源：Chemical Communications, 2016, 52(15): 3251-3253.

DOI：10.1039/c5cc10416e

• N-LINKED GLYCOPEPTIDES
• SELECTIVE ENRICHMENT
• MAGNETIC NANOPARTICLES
• MASS-SPECTROMETRY
• CHROMATOGRAPHY
• EFFICIENT
• GLYCOPROTEINS
• CHITOSAN
• CAPTURE
• MATRIX

CS@PGMA@IDA nanomaterials were facilely synthesized, the zwitterion polymer surface PGMA@IDA endows the nanomaterial with biocompatibility, excellent hydrophilic properties and a large amount of functional groups on the polymer chains that can selectively bind to glycopeptides based on hydrophilic interaction.

• 出版日期2016
• 单位青海省人民医院; 中日友好医院; 北京大学