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摘要
An automated sleep staging based on analyzing long-range time correlations in EEG is proposed. These correlations, indicating time-scale invariant property or self-similarity at different time scales, are known to be salient dynamical characteristics of stage succession for a sleeping brain even when the subject suffers a destructive disorder such as Obstructive Sleep Apnea (OSA). The goal is to extract a set of complementary features from cerebral sources mapped onto the scalp electrodes or from a number of denoised EEG channels. For this purpose, source localization/extraction and noise reduction approaches based on Independent Component Analysis were used prior to correlation analysis. Feature extracted segments were then classified in one of the five classes including WAKE, STAGE1, STAGE2, SWS and REM via an ensemble neuro-fuzzy classifier. Some techniques were employed to improve the classifier's performance including Scaled Conjugate Gradient Method to speed up learning the ANFIS classifiers, a pruning algorithm to eliminate irrelevant fuzzy rules and the 10-fold cross-validation technique to train and test the system more efficiently. The performance of classification for two strategies including (1) feature extraction from effective cerebral sources and (2) feature extraction from selected channels of denoised EEG signals was compared and contrasted in terms of training errors and test accuracies. The first and second strategies achieved 92.23 and 88.74% agreement with human expert respectively which indicates the effectiveness of the staging system based on cerebral sources of activity. Our results further indicate that the misclassification rates were almost below 10%. The proposed automated sleep staging system is reliable due to the fact that it is based on the underlying dynamics of sleep staging which is less likely to be affected by sleep fragmentations occurred repeatedly in OSA.
- 出版日期2018-3
