Design, Synthesis, and Characterization of Self-assembled Peptide Nanostructures toward Peptide-directed Biomineralization

作者:Tomizaki Kin ya*; Kotera Tatsuki; Naito Hideki; Wakizaka Shota; Yamamoto Shin ichi
来源:Chemistry Letters, 2011, 40(7): 699-701.
DOI:10.1246/cl.2011.699

摘要

There is increasing interest in nanostructures and in the molecular design of building blocks which self-assemble into nanoscaled intelligent materials. We outline a method for controlling the nanostructures of amphiphilic nonapeptides by changing the pH of the aqueous medium. A lysine residue on the hydrophilic face of the peptide plays a critical role as a morphology-control unit. This self-assembling peptide may, therefore, find application as a template for peptide-directed biomineralization.

  • 出版日期2011-7-5