A new class of C-2 chiral photodimer ligands for catalytic enantioselective diethylzinc addition to arylaldehydes

作者：Ueda Yuki; Yagishita Fumitoshi; Ishikawa Hiroki; Kaji Yuki; Baba Nozomi; Kasashima Yoshio; Mino Takashi; Sakamoto Masami^*

来源：Tetrahedron, 2015, 71(36): 6254-6258.

DOI：10.1016/j.tet.2015.06.084

• C-2 chiral ligand
• Photodimer
• Asymmetric ethylation
• Diethylzinc
• Diol ligand

A new class of C-2 chiral materials was easily prepared by the photodimerization reaction of (R)-N-phenethy1-2-chromonecarboxamide followed by recrystallization. Reduction of the photodimer gave the corresponding alcohol stereoselectively. Both C-2 chiral materials worked effectively as ligands for enantioselective ethylation of arylaldehydes using diethylzinc.

• 出版日期2015-9-9