Neonates, antibiotics and the microbiome

作者:Thanabalasuriar Ajitha*; Kubes Paul
来源:Nature Medicine, 2014, 20(5): 469-470.
DOI:10.1038/nm.3558

摘要

As babies leave their mothers%26apos; wombs, they are colonized by commensal bacteria. A new study shows that these microbes in a newborn%26apos;s gut can promote an increase in circulating neutrophils that can guard the body from infections. Altering a neonate%26apos;s gut microbiota with perinatal antibiotic treatment can impair neutrophils, leaving the newborn vulnerable to attack by harmful bacteria (pages 524-530).

  • 出版日期2014-5