Multi-physics MRI-based two-layer fluid-structure interaction anisotropic models of human right and left ventricles with different patch materials: Cardiac function assessment and mechanical stress analysis

作者：Tang, Dalin^*; Yang, Chun; Geva, Tal; Gaudette, Glenn; del Nido, Pedro J.

来源：COMPUTERS & STRUCTURES, 2011, 89(11-12): 1059-1068.

DOI：10.1016/j.compstruc.2010.12.012

• Right ventricle
• Congenital heart disease
• Heart model
• Dacron scaffold patch
• Fluid-structural interaction

Multi-physics right and left ventricle (RV/LV) fluid-structure interaction (FSI) models were introduced to perform mechanical stress analysis and evaluate the effect of patch materials on RV function. The FSI models included three different patch materials (Dacron scaffold, treated pericardium, and contracting myocardium), two-layer construction, fiber orientation, and active anisotropic material properties. The models were constructed based on cardiac magnetic resonance (CMR) images acquired from a patient with severe RV dilatation and solved by ADINA. Our results indicate that the patch model with contracting myocardium leads to decreased stress level in the patch area, improved RV function and patch area contractility.

• 出版日期2011-6
• 单位北京师范大学