Assessing Patients With hepatocellular Carcinoma Meeting the Milan Criteria: Is Liver 3 Tesla MR With Gadoxetic Acid Necessary in Addition to Liver CT?

作者：Cha Dong Ik; Lee Min Woo^*; Kim Young Kon; Kim Seong Hyun; Park Hyun Jeong; Rhim Hyunchul; Lim Hyo K

来源：Journal of Magnetic Resonance Imaging, 2014, 39(4): 842-852.

DOI：10.1002/jmri.24237

• magnetic resonance imaging
• carcinoma
• hepatocellular
• neoplasm staging

PurposeTo determine the added value of 3 Tesla liver MR in patients with hepatocellular carcinoma (HCC) within the liver computed tomography (CT) -based Milan criteria. %26lt;br%26gt;Materials and MethodsLiver CT and MR images of 130 patients with HCC within the Milan criteria based on liver CT were retrospectively reviewed. The number of MR-diagnosed HCCs and that of high risk hypervascular nodules (HRHNs), the effect of obtaining MR on patient management and CT appearances of MR-diagnosed HCCs and those of HRHNs were evaluated. Independent predictor for diagnosing additional HCCs on liver MR was analyzed. %26lt;br%26gt;ResultsA total of 18.5% (24/130) of patients had additional 39 HCCs on MR, with a 5.4% (7/130) dropout rate from the Milan criteria. 28.5% (37/130) of patients had additional 78 HRHNs. Overall, 39.2% (51/130) of patients required changes in management. The common CT appearances of MR-diagnosed HCCs were arterial enhancing lesions 0.5cm (38.4%, 15/39), low density nodules %26lt; 1.5 cm (30.8%, 12/39) and invisibility (28.2%, 11/39). For MR-diagnosed HRHNs, 55.1% (43/78) were invisible on CT. The presence of inconclusive lesions on CT was an independent predictor for diagnosing additional HCCs on MR. %26lt;br%26gt;ConclusionFor patients with HCCs within the Milan criteria on liver CT, liver MR may be necessary to detect additional HCCs and HRHNs. J. Magn. Reson. Imaging 2014;39:842-852.

• 出版日期2014-4