A non-nucleoside triphosphate for powering kinesin-microtubule motility with photo-tunable velocity

作者:Perur Nishad; Yahara Masao; Kamei Takashi; Tamaoki Nobuyuki*
来源:Chemical communications, 2013, 49(85): 9935-9937.
DOI:10.1039/c3cc45933k

摘要

Three non-nucleoside triphosphates, one containing an azobenzene moiety, power a kinesin-microtubule system with high motile activity, with an observed maximum velocity of almost half of that obtained with ATP. The cis-trans photoisomerization of the azobenzene unit allows reversible and repeated control over the motile properties of kinesin.

  • 出版日期2013